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New Orleans, La – The (6-2) Saints host the (4-5) San Francisco 49ers at the Mercedes-Benz Superdome on Sunday afternoon.
New Orleans is on a 5 game win streak, coming off of a dominating victory over Tampa Bay in Week 9.
The Saints are double-digit favorites over a depleted 49ers team. Quarterback Jimmy Garoppolo, TE George Kittle, RB Raheem Mosters and DE Nick Bosa are not available for Week 10.
